Certified Registered Nurse Infusion (CRNI) Practice Exam

What is a serious adverse event associated with Daptomycin that should be reported?

1. Rash

2. Muscle pain

3. Diarrhea

4. Nausea

The correct answer is: Muscle pain

Muscle pain is a serious adverse event associated with Daptomycin that warrants reporting due to its potential indication of a more severe condition known as rhabdomyolysis. This condition involves the breakdown of muscle tissue that can lead to kidney damage and other significant health issues. Daptomycin can cause elevated levels of creatine phosphokinase (CPK), which is a marker of muscle damage. Monitoring and reporting muscle pain, especially if it is accompanied by elevated CPK levels, is crucial in ensuring patient safety and effective management of Daptomycin therapy. While rash, diarrhea, and nausea can occur as side effects, they are generally not classified as serious adverse events in the context of Daptomycin. Rashes can be mild and often resolve without significant treatment. Diarrhea and nausea may occur in many medications but are not typically reflective of life-threatening conditions associated with Daptomycin. Hence, muscle pain stands out as a critical symptom requiring careful attention and prompt reporting to ensure patient safety.